A Safety and Tolerability Study of 10XB-101 Injection in Adult Subjects With Submental Fat

Inclusion Criteria: * Subject is a male or non-pregnant female 18 to 65 years old. * Subject has provided written informed consent. * Subject has qualifying Submental Fat evaluation score. * Subject has had a stable body weight for the past 6 months prior to starting study. * Subject is willing to undergo test article injections as directed, comply with study instructions, and commit to all follow-up visits for the duration of the study. Exclusion Criteria: * Subject is pregnant, lactating, or is planning to become pregnant during the study. * Subject has loose skin in the submental area, diffuse SMF, or prominent platysmal bands at rest that may interfere with evaluation of localized fat, in the opinion of the investigator. * Subject has had any prior treatment for SMF (e.g., deoxycholic acid, cryotherapy, liposuction, surgery). * Subject has any medical condition that affects clotting and/or platelet function * Subject has a history of allergy or sensitivity to polidocanol or any of the other ingredients in the test articles.