Biomonitoring of Internal Exposure to MNPLs, and Its Effects, in Blood of Patients With Chronic Kidney Disease (CKD)

Inclusion Criteria for Chronic Kidney Disease (CKD) submitted to Hemodialysis: * Participant submitted to hemodialysis for more than 3 months * Between 18 and 85 years old * Stable haemoglobin (more than 10 gr/dl) * Absence of infectious disease at the date of sample collection and for a period of more than two weeks * Absence of active neoplasia * Stable vascular access Inclusion Criteria for Chronic Kidney Disease (CKD) pre-dialysis: * No hemodialysis treatment * Between 18 and 85 years old * Stable haemoglobin (more than 10 gr/dl) * Glomerular filtration ≤ 20 ml/min * Absence of infectious disease at the date of sample collection and for a period of more than two weeks * Absence of active neoplasia Inclusion Criteria for controls : * Between 18 and 85 years old (paired by gender, age and lifestyle to the CKD patients) * Absence of chronic kidney disease or dialysis treatment * Absence of chronic pathology (including neoplasia) * Absence of infectious disease at the date of sample collection and for a period of more than two weeks * Spanish residence Exclusion Criteria for both groups of CKD patients: * Clinical instability * Life expectancy of less than 12 months * Coagulation system disorders * Participation in other clinical study * Pregnancy * Unsigned informed consent Exclusion criteria for controls: * Participation in other clinical study * Pregnancy * Unsigned informed consent