In connection with the transition to the 8th version of the classification of lung cancer according to the TNM system, there are currently no precise epidemiological data on stage III NSCLC, clinical characteristics of patients in this group, approaches to therapy and treatment results in the Russian Federation. The published statistics only provide information on the overall incidence of stage III lung, trachea and bronchial cancer, which is about 40%. This observational study will make it possible to characterize the Russian population of stage III non-small cell lung cancer patients, approaches to choosing a treatment option for stage III NSCLC and the outcomes of this treatment in real clinical practice.
Study Type
OBSERVATIONAL
Enrollment
1
National Medical Research Center of Oncology. N. N. Blokhin
Moscow, Russia
Examine clinical and morphological groups
* gender ratio (husband, wife) * smoking status (smoker, non-smoker, past smoker) * proportional distribution: squamous cell, adenocarcinoma, dimorphic cancer, others) * how many patients with mediastinal lymph node involvement: (N0, N1, N2, N3) * detection frequency: PDL (PDL \<1, PDL\> 1, PDL \<49, PDL\> 50), EGFR (EGFR + (19.24 exon) EGFR-), (ALK +, ALK -), (ROS-1 +, ROS-1 -) Get information about regional algorithms * Variants of treatment tactics: Percentage: a. Surgery v. Chemotherapy -Diagnostic algorithm: a. Morphological verification frequency b. The frequency of confirmation of metastatic lesions within the thoracic lymph nodes c. F
Time frame: 10/01/2023
Explore clinical approaches
* Percentage of treatment options depending on: a. histological type * squamous * adenocarcinoma * dimorphic * 3 A st * 3B st
Time frame: 10/01/2023
Diagnostic algorithm:
v. from a variant of molecular genetic disorders * PDL \<1 * PDL\> 1 * PDL \<49 * PDL\> 50 * EGFR +
Time frame: 10/01/2023
Percentage of treatment options
from functional status * ECOG 1 1. only surgical treatment 2. surgical + drug treatment 3. surgical + drug treatment + radiation therapy 4. drug treatment 5. drug treatment + radiation therapy 6. radiation therapy * ECOG 2 1. only surgical treatment 2. surgical + drug treatment 3. surgical + drug treatment + radiation therapy 4. drug treatment 5. drug treatment + radiation therapy 6. radiation therapy * ECOG 3 1. only surgical treatment 2. surgical + drug treatment 3. surgical + drug treatment + radiation therapy 4. drug treatment 5. drug treatment + radiation therapy 6. radiation therapy
Time frame: 10/01/2023
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