Precise identification of the atrial fibrosis is essential for successful catheter ablation of atrial arrhythmias in patients with atrial fibrillation. Voltage mapping of endocardial electrograms is currently used to delineate the anatomical substrate, but this is influenced by the direction of the activation wave front and is limited by the patient-specific thresholds. Mapping of local myocardial electrical impedance may overcome these limitations.
Clinical series: Patients with atrial arrythmias undergoing catheter ablation of these will be submitted to mapping of both voltage and tissue impedance. Likewise, the accuracy of the two maps identifying the extent of the substrate will be assesssed by gadolinium imaging. The impedance system is already constructed and certified for clinical research use.
Study Type
OBSERVATIONAL
Enrollment
15
Patients will be submitted to mapping of both voltage and tissue impedance.
Hospital de la Santa Creu i Sant Pau
Barcelona, Spain
RECRUITINGComparative detection of atrial scar by voltage mapping
Voltage will be measured at different sites of the atrial scar and healthy tissue.
Time frame: 30 minutes
Comparative detection of atrial scar by impedance mapping
Myocardial local impedance spectroscopy will be measured at different sites of the atrial scar and healthy tissue.
Time frame: 30 minutes
Comparative detection of atrial scar by gadolinium enhanced MR imaging
Intensity of gadolinium will be measured at different sites of the infarct scar and healthy tissue
Time frame: 30 minutes
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.