This is a single-centre pilot study of a non-invasive auditory stimulation during sleep in participants with temporal lobe epilepsy.
The primary objectives will be to pilot the use of home-based auditory stimulation during sleep in 10-20 participants with temporal lobe epilepsy using wireless devices.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
17
50ms of low volume pink noise delivered during slow wave sleep
Cardiff and Vale UHW, Neurology department, ward C4, video-EEG monitoring unit
Cardiff, United Kingdom
Change in EEG waveform amplitude
Does the acoustic sound delivery alter EEG waveform amplitude of slow wave sleep
Time frame: 5 seconds after stimulus
Change in Serial Reaction Time Task memory test
Does the delivery of acoustic sounds alter post-sleep preformance on the above task
Time frame: Baseline and following day
Change in Paired Associates Learning memory test
Does the delivery of acoustic sounds alter post-sleep preformance on the above task
Time frame: Baseline and following day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.