Probiotic in Treatment of Adult Patients With Drug-resistant Epilepsy

Mazandaran University of Medical Sciences42 enrolled

Overview

This study is a randomized, double-blind parallel group placebo-controlled clinical trial with the aim of investigating the effect of probiotic versus placebo on drug-resistant adult patients with epilepsy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Epilepsy Treatment

Interventions

ProbioticDRUG

Each probiotic capsule contained combination of lactobacillus and Bifidobacterium species.

Eligibility

Sex: ALLMin age: 16 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: Drug resistant epilepsy Exclusion Criteria: * Hypersensitivity to probiotic * Acute pancreatitis * Pregnancy * Breastfeeding * Being under treatment with corticosteroids * Being under treatment with antibiotics during 2 months before enrollment * Need for antibiotic therapy during the study * Change in anti-seizure medication within the month before enrollment

Locations (1)

Bu Ali Sina Hospital

Sari, Mazandaran, Iran

Outcomes

Primary Outcomes

Change in seizure frequency

Time frame: 12 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.