Many patients develop autoimmune diseases after covid-19 vaccination, whether related to the vaccination or not, is still under study. This study will describe potential flare of ARD after COVID-19 vaccination, whether it leads to activity or new MSK manifestations development.
-In this study: patients with known diagnosed rheumatic diseases who are vaccinated (one or full doses) of any type of COVID-19 vaccines will be enrolled. new ARD and prevalence of different MSK manifestations after covid-19 vaccinations also will be reported. The prevalence of flare of ARD after covid-19 vaccinations will be dteremined. Also we will compare between different types and doses of covid-19 vaccinations in inducing ARD or flares. Study Design: Cross sectional study Target population: any patient with pre-existing received any vaccination against covid-19 visiting rheumatology outpatient clinic. -any patient develops MSK manifestations after covid-19 vaccination. The disease activity sataus will be measured according to the type of rheumatic disease. For RA , disease activity score28 will be used, in lupus: SLEDAI, in Behcet : BDCAF, in SpA: BASDAI.
Study Type
OBSERVATIONAL
Enrollment
500
different types of covid-19 vaccinations.
Kasr Alainy Hospital
Cairo, Egypt
RECRUITING-Prevalence of new ARD after covid-19 vaccinations
any ARD
Time frame: 3 moths
prevalence of flare of ARD after covid-19 vaccinations
flare of any manifestations of the disease
Time frame: 3 months
Prevalence of non-specific MSK symptoms after Covid-19 vaccine.
any MSK symptoms
Time frame: 3 months
Correlation of the MSK to the 1st and 2nd Covid vaccine dose
Correlation of the MSK to the 1st and 2nd Covid vaccine dose
Time frame: 3 months
comparison between different type of covid-19 vaccine in inducing ARD or flare up.
any type of flare
Time frame: 3 months
disease activity status in the patients who developed the ARD symptoms before and after the vaccine.
activity assessed by disease activity scores
Time frame: 3 months
Any correlation between the appearance of MSK symptoms and the patient's medications
current medications
Time frame: 3 months
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