Study of Imaginomics Predicting Early Surgical Rates in Crohn's Disease

Sixth Affiliated Hospital, Sun Yat-sen University300 enrolled

Overview

Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic intestinal recurrent inflammatory disease involving the entire digestive tract. Most CD patients require surgery for complications, including stenosis, perforation, and severe intestinal bleeding. Predicting early-onset surgery risk is of great importance to assist launching of therapeutic strategies. We aim to establish a digital prognostic model and nomogram using radiomics, which will help clinical practice.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Crohn Disease Prognostic Model Radiomics

Interventions

CTE examinationOTHER

each patients should have undergone CTE examination

Medical Language ↔ Plain English

Inclusion Criteria: patients with a confirmed diagnosis of CD; a follow-up more than 1 year; without previous CD-associated intestinal surgeries; complete data of CTE. Exclusion Criteria: patients without a confirmed diagnosis of CD; with incomplete data and a follow-up less than 1 year; patients have previous intestinal surgeries; patients who have never undergone CTE examination.

Outcomes

Primary Outcomes

percentages of surgery at one-year after diagnosis

Time frame: 2017-2021

Study of Imaginomics Predicting Early Surgical Rates in Crohn's Disease

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts