Variability of Physical Assessments in an Older Population That is Overweight or Obese

Versanis Bio, Inc.58 enrolled

Overview

Variability of physical assessments in an older population that is overweight or obese.

The purpose of this study is to understand difficulty in obtaining physical assessment measurements and assess the variability of these assessments when performed by people who are overweight or obese. Data collected in this protocol will be used to inform the design of future clinical studies.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Obesity Aging

Interventions

Short Performance Physical Battery (SPPB Test)BEHAVIORAL

The SPPB includes balance stands, a 4-meter walk and 5 timed chair stands.

30 Second Chair Stand Test (30CST)BEHAVIORAL

The 30CST measures the number of times a person can rise from a seated to standing position within 30 seconds.

Hand grip dynamometryBEHAVIORAL

Grip strength is used as a marker of overall muscle strength.

Eligibility

Sex: ALLMin age: 45 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * A written informed consent must be obtained before any study-related assessment is conducted. * Men and women aged ≥ 45. * BMI ≥ 30 or BMI ≥ 27 with one or more obesity-associated comorbidities (e.g. hypertension, cardiovascular disease, hyperlipidemia, elevated fasting blood sugar levels, sleep apnea). * Participants must be able to communicate well with the Investigator and comply with the study requirements. Exclusion Criteria: * Participant weight \> 150 kg. * Systolic blood pressure \< 90 or \> 180 or diastolic blood pressure \<50 or \>100. * Heart rate ≤ 50 or ≥ 100. * Unstable medical condition that would put the participant at risk by performing the study assessments. * Chronic medical condition rendering participants unable to perform the assessment, e.g., severe knee osteoarthritis.

Locations (2)

CNS Healthcare

Jacksonville, Florida, United States

CNS Healthcare

Orlando, Florida, United States

Outcomes

Primary Outcomes

To assess the variability of Short Physical Performance Battery (SPPB, scored from 0-12) results within and between participants.