An unanticipated difficult laryngoscopy is associated with serious airway-related complications. The investigators developed a deep learning-based model that predicts a difficult laryngoscopy (Cormack-Lehane grade 3-4) from a cervical spine lateral X-ray using data from 14,135 patients undergoing thyroid surgery. This model showed excellent predictive performance, which was higher than that of other deep learning architectures. In this study, the investigators prospectively validate the model for predicting a difficult laryngoscopy and compare predictive power with clinical airway evaluation.
Predicting a difficulty of a laryngoscopy is important for patient safety, as an unanticipated difficult laryngoscopy is associated with serious airway-related complications, such as brain damage, cardiopulmonary arrest, or death. Although clinical predictors, such as the modified Mallampati classification, thyromental distance, inter-incisor gap, and the upper lip bite test, are used for airway evaluation in clinical practice, these indicators have low sensitivity and large inter-assessor variability and require patient cooperation. The investigators developed a deep learning-based model that predicts a difficult laryngoscopy from a cervical spine lateral X-ray using data from 14,135 patients undergoing thyroid surgery. And this study is under submission. This deep learning model showed the highest performance in predicting difficult laryngoscopy compared to other deep learning models (VGG-Net, ResNet, Xception, ResNext, DenseNet, and SENet) with a sensitivity of 95.6%, a specificity of 91.2%, and an area under ROC curve (AUROC) of 0.972. However, as the model was a retrospective design using existing medical records, the presence or absence of cricoid pressure to obtain the optimal laryngoscopy was not evaluated, and not compared with airway evaluations. In this study, the investigators prospectively validate the model for predicting a difficult laryngoscopy and compare predictive power with clinical airway evaluation. If this study prospective confirm our results, this approach can be helpful in improving patient safety and preventing airway-related complications through objective and accurate airway evaluation.
Study Type
OBSERVATIONAL
Enrollment
367
The deep learning model uses the input of preprocessed C-spine lateral X-ray images and outputs the level of difficulty of a laryngoscopy. The easy laryngoscopy is defined as a combination of the Cormack-Lehane grades 1-2 and the difficult laryngoscopy is defined as a combination of grades 3-4. In addition, before general anesthesia, airway evaluations related to the difficulty of laryngoscopy are performed and the results are compared with the actual level of difficulty.
Seoul National University Hospital
Seoul, Select A State Or Province, South Korea
RECRUITINGThe area under the receiver operating characteristic curve of deep learning model and airway evaluations for predicting a difficult laryngoscopy.
Difficult laryngoscopy definition: Cormack-Lehane grade 3 or 4 . Airway evaluations: Inter-incisor gap (millimeter), thyromental distance (millimeter), thyromental height (millimeter), sternomental distance (millimeter), and modified Mallampati class
Time frame: during induction of anesthesia
The area under the receiver operating characteristic curve of deep learning model and airway evaluations for predicting a difficult intubation.
Difficult intubation: Intubation Difficulty Scale (score)
Time frame: during induction of anesthesia
Other Performances for predicting a difficult laryngoscopy of deep learning model.
sensitivity (percent), specificity(percent), Positive predictive value(percent), Negative predictive value (percent), F1-score, and balanced accuracy.
Time frame: during induction of anesthesia
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.