The aim of this study is to determine the efficacy of an oral nutraceutical with probiotics in restore vaginal health.
After being informed about the study, all patients meeting the inclusion/exclusion criteria and giving written informed consent will receive a nutraceutical containing L. rhamnosus, L. plantarum and L. crispatus once daily.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
32
Lactobacillus rhamnosus BPL 205, Lactobacillus plantarum BPL207 and Lactobacillus crispatus BPL209
HM Fertility Centter Vallés
Alcalá de Henares, Madrid, Spain
Rectal and vaginal colonization
Rectal and vaginal colonization will be evaluated by measuring massive sequencing of 16SrRNA gen
Time frame: 10 weeks
Autoinmune capacity
Autoinmune capacity will be evaluated by measuring plasma levels of IL-10, TNF- alpha and IL-10
Time frame: 10 weeks
Antioxidant effect
Antioxidant will be evaluated by measuring Total Antioxidant Capacity (TAC) and Malondialdehyde
Time frame: 10 weeks
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