Adaptation to resistance exercise requires maximal rates of muscle protein synthesis, which can be achieved with post-exercise ingestion of \~20g of protein. These recommendations are based on studies in males and responses in females may vary. Muscle recovery is related to the ability to build new muscle protein from amino acids (muscle protein synthesis). This response is thought to be impacted in females by hormones that fluctuate across different phases of the menstrual cycle. However, the effect of menstrual cycle phase on muscle protein synthesis is not known.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
28
One of three protein doses provided
Different phase of the menstrual cycle
University of Exeter
Exeter, Devon, United Kingdom
Muscle protein synthesis
The rate of synthesis of new muscle protein
Time frame: 7.5 hours
Plasma amino acid kinetics
The appearance of amino acids in the circulation.
Time frame: 7.5 hours
Serum insulin concentrations
Basal and postprandial concentrations of serum insulin
Time frame: 7.5 hours
Blood flow
Basal and postprandial blood flow using ultrasound
Time frame: 7.5 hours
Sex hormone concentrations
Serum oestrogen and progesterone
Time frame: 5 minutes
Gene expression
Gene expression of muscle samples using RNA extraction
Time frame: 7.5 hours
Blood glucose
Basal and postprandial concentrations of blood glucose
Time frame: 7.5 hours
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