Aesthetic Outcomes of Oncoplastic Breast Surgery for Breast Cancer in the Upper Inner Quadrant

Inclusion Criteria: * Signed the informed consent. * Female aged between 18 and 70 years. * Pathologically diagnosed operable breast cancer. * WHO Eastern Cooperative Oncology Group (ECOG) performance status of 0-1. * Cancer located in the upper inner quadrant; Single tumor or multiple tumors in the same quadrant. * The important organ functions meet the following criteria: * WBC \>=3.0 x 10\^9/L; Neutrophilic granulocytes \>=1.5×10\^9/L; Platelet \>=100 x 10\^9/L; Hb \>=9 g/dL; * Total bilirubin no more than 1.5 times the normal upper limit (ULN); AST and ALT no more than 1.5 times ULN; AKP no more than 2.5 times ULN; * Serum creatinine no more than 1.5 times ULN or Clearance rate of creatinine \>= 60ml/min; * Thyroid stimulating hormone (TSH) \<= ULN (T3, T4 levels need to be detected simultaneously if abnormalities, the patient can be included if T3, T4 levels is normal); * LVEF basement \>= 50%. * Adjust to the criteria of breast conserving surgery. Exclusion Criteria: * Multifocal or multicentric disease. * Tumor localized in the central quadrant or the distance to the nipple \< 2 cm； * Diffused calcifications with fine plemorphic or fine linear or fine-linear branching morphology. * The ratio of tumor to breast \> 20%; * The diameter of tumor is up to 4 cm; * Women in the early or intermediate stage of pregnancy; * Prior history of breast radiation; * Any severe comorbidities, inability to give informed consent or unavailability for follow-up.