The primary purpose of this study is to examine the efficacy of family meal frequency as an intervention target in addressing the primary prevention of CVD.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
42
A family-based multicomponent lifestyle modification intervention with the goal to increase the frequency of family meals and meet physical activity recommendations.
A family-based multicomponent lifestyle modification intervention with the goal to increase the consumption of fruits and vegetables and and meet physical activity recommendations.
University of Delaware, Energy Balance and Nutrition Laboratory
Newark, Delaware, United States
Change from baseline in diet quality.
The Healthy Eating Index is a score ranging from 0-100 with higher scores indicating greater adherence to the Dietary Guidelines.
Time frame: Baseline and Months 2, 6, 8 and 10
Change from baseline in body mass index z-scores (zBMI)
Body mass index z-scores (zBMI) will be calculated using Centers for Disease Control and Prevention growth charts. Height will be measured in centimeters and weight will be measured in kilograms and used to calculate BMI as kilograms/meter squared.
Time frame: Baseline and Months 2, 6, 8 and 10
Change from baseline in blood pressure
Both systolic and diastolic blood pressure.
Time frame: Baseline and Month 6
Change from baseline in fasting insulin
Measure of insulin in the blood after fasting.
Time frame: Baseline and Month 6
Change from baseline in fasting glucose
Measure of blood sugar (glucose) after fasting.
Time frame: Baseline and Month 6
Change from baseline in lipid levels
Nuclear magnetic resonance (NMR) measures of lipoprotein (low-density lipoprotein \[LDL\], high-density lipoprotein \[HDL\], very-low density lipoprotein \[VLDL\]) particle number and size will be assessed.
Time frame: Baseline and Month 6
Change from baseline in pulse wave analysis.
PWA will be assessed by a central aortic pressure waveform synthesized from the measured brachial artery pressure waveform via a standard blood pressure cuff inflation/deflation and blood pressure monitoring.
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Time frame: Baseline and Month 6
Change from baseline in carotid-to-femoral pulse wave velocity (PVW)
Carotid-to-femoral PWV will be measured by simultaneously recording electrocardiography (ECG) and a carotid or femoral pressure waveform via a standard blood pressure cuff inflation/deflation and blood pressure monitoring. The distance from the carotid measurement point to the sternal notch will be subtracted from the distance from the sternal notch to the femoral measurement point and used as propagation distance. PWV will be calculated as propagation distance/time delay. PWV is a measure of regional stiffness of the aorta.
Time frame: Baseline and Month 6
Change in baseline in flow-mediated dilation (FMD)
The FMD technique will be employed by assessing the diameter and blood flow velocity of the artery located in the upper arm via ultrasonography. FMD will be used as a measure of endothelial-dependent vessel function and will be expressed as a percent change from baseline, normalized for shear rate calculated from blood flow velocity and vessel diameter data.
Time frame: Baseline and Month 6