Assessment of Safety , Clinical Efficacy with QLETLI in Non-infectious Uveitis (UV)

Inclusion Criteria: * Patients voluntarily participated in the study and signed informed consent * Aged between 18 and 70 (including threshold), male or female; * Diagnosis of non-infectious intermediate, posterior, or total uveitis in at least one eye; * Received maintenance therapy (oral prednisone 10-60mg/day or equivalent glucocorticoid for ≧2 weeks before screening, and no dose adjustment from screening to baseline; * At baseline, at least one eye was diagnosed with active uveitis, presenting as meeting at least one of the following criteria: active inflammatory chorioretinal and/or inflammatory retinal vasculopathy; Cell grade of anterior chamber ≧2+; Degree of vitreous turbid ≧2+; * Negative serum pregnancy test results of women of childbearing age during screening visits; Exclusion Criteria: * Patients with the following eye conditions: * Patients with simple anterior uveitis; * Uveitis with macular edema as the only manifestation; * is confirmed or suspected infectious uveitis (including but not limited to the following causes of infectious uveitis, tuberculosis, cytomegalovirus, lyme disease, toxoplasmosis, human, T, Whipple's disease virus type 1 infection, herpes zoster virus and herpes simplex virus) or disguise syndrome (for example: eye trauma, lymphoma, malignant tumor, or surgery, etc.); * Uncontrolled glaucoma, defined as intraocular pressure higher than 25 mmHg after drug treatment, or optic nerve damage; * Best corrected visual acuity of less than 20 letters in at least one eye at baseline; * With other fundus diseases (such as fertile or serious non fertile diabetic retinopathy or diabetic retinopathy with clinical significance of macular edema, retinal vein occlusion, macular degeneration, age, sex, blood vessel patterns change, the pathological myopia, retinal detachment, macular hole, toxoplasmosis, optic nerve disease, etc.); * Demyelinating disease (including myelitis and optic neuritis) or a history of neurology suggesting symptoms of demyelinating disease (including but not limited to optic neuritis); * Refractive media opacity or pupil failure that significantly interferes with visual acuity detection, anterior segment and fundus assessment; * One-eyed patients deemed unsuitable for inclusion by the investigator; * Peribulbar, intravitreal or subocular corticosteroid injections were given within 30 days prior to screening; * Posterior capsulotomy was performed within 30 days prior to screening; * Cataract surgery is expected within 90 days prior to screening or during the study period; * An intravitreal injection of anti-VEGF therapy (e.g., raizumab, apecivir, or Combocept) within 90 days prior to baseline; * Ozurdex implants (dexamethasone implants) were performed within 6 months prior to baseline; * Treatment with intravitreal injection of methotrexate within 90 days prior to baseline; * Had been treated with vitreous Retisert (glucocorticoid implant) or had complications with the implant during the 36 months prior to baseline; Removal of Retisert within 90 days prior to baseline or complications of removal. * Having any of the following general conditions: * Subjects meet any of the following criteria associated with latent or active tuberculosis (TB) infection: . A history of active TB ≤ 3 years before screening (but can also be included if it is \> 3 years and documented completion of adequate treatment); B. Signs or symptoms suggestive of active TB at the time of screening in the history and/or physical examination; C. Recent close contact with someone with active TB; D. If a TB infection T-cell test is positive at the time of screening, subjects will be excluded from the study if their first TB infection T-cell test is inconclusive. For suitable standards has been completed before screening latent TB treatment and no other risk factors, imaging findings, or support the latent or signs of active TB specific subjects, for positive or uncertain results may be the exception handling, researchers with the qualified physician judgment, tuberculosis (including extrapulmonary) risk, decision and discuss with bidders; * Positive hepatitis C antibody during screening; Or HIV antibody positive; Or treponema pallidum antibody positive; * Symptoms of severe, progressive or uncontrollable kidney, liver, blood, gastrointestinal, lung, cardiovascular, neurological or brain disease. The investigator felt that participating in the study placed patients at unacceptable risk. * Patients with malignant tumors. * Patients with moderate to severe heart failure (New York Heart Society Grades 3-4). * History of severe allergy or anaphylactoid reaction to monoclonal antibodies. * Prior treatment with anti-TUMOR necrosis factor TNF or other biological agents with potential therapeutic effect for uveitis (excluding intravitreal anti-VEGF drugs). * During the 30 days prior to baseline, the combined dose of other immunosuppressant therapy increased or did not meet any of the following conditions: methotrexate MTX≤25mg/ week; Cyclosporine ≤4 mg/kg/ day; Mycophenolate (or equivalent dose of mycophenolate) ≤2g/ day; Azathioprine ≤175 mg/ day; Tacrolimus oral ≤8 mg/ day. * Received clinical trial drug intervention within 3 months prior to screening. * Received any live vaccine within 3 months prior to receiving the first dose of the study drug, or planned to receive live vaccine during the study period. * There are contraindications to dilatation drugs. * Patients judged unsuitable for inclusion by other investigators