Effectiveness of Photo-biomodulation in the Treatment of Chemotherapy Induced Mucositis

N/ACompletedNCT05181943

Alexandria University44 enrolled

Overview

The aim of the current study was to study the effect of diode laser in the treatment of chemotherapy induced mucositis in young patients suffering from leukemia

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Mucositis

Interventions

Simpler diode laserDEVICE

Non-contacting irradiation for 30 seconds on three intraoral sites repeated four times

Conventional symptomatic treatmentDRUG

Conventional treatment using oracure, BBC spray, miconaz three times daily

Eligibility

Sex: ALLMin age: 2 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * children diagnosed with mucositis and receiving chemotherapy Exclusion Criteria: * diabetes * trismus

Locations (1)

Faculty of Dentistry, Alexandria University

Alexandria, Egypt

Outcomes

Primary Outcomes

Self-reported pain level

Participants were asked to report the degree of pain. This was assessed using the visual analogue scale (VAS) which ranges from zero (lowest score) to 10 (highest score). Higher scores indicate higher pain level.

Time frame: up to 2 weeks

Oral mucositis lesion size

This was assessed using the World Health Organization oral mucositis lesion score Grade 0: no oral mucositis. Grade1: Presence of soreness and erythema. Grade 2: Presence of painful erythema and ulcerations that do not affect the patient solid food intake. Grade3: Confluent ulceration that affect the solid food intake and require liquid diet. Grade 4: The patient requires parenteral nutrition.

Time frame: up to 2 weeks

Data from ClinicalTrials.gov

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