A prospective observational study of pregnancy outcomes at advanced maternal age among primigravida which include maternal ,fetal, obstetric and perinatal outcomes
The investigator will have 2 groups of primigravida , the first group will be presented by 50 women aged 35 y or more and the second group will be presented by 50 women aged 20 y to 34 y The first group will be also divided into 2 subgroups : group (1A ) aged 35 y to 40 y and group (1B) aged above 40 y The investigator will compare the outcomes between the two group , also comparing the outcomes between women with spontaneous pregnancy and those using ART ( Assisted Reproductive Technology ) The participants will undergo routine investigations at the first antenatal visit and a monthly ultrasound examination until delivery The participants will be screened for gestational diabetes mellitus using oral glucose tolerance test between 24 :34 weeks of pregnancy The participants will be screened for gestational hypertension after 20 weeks of pregnancy Obstetric outcomes will be recorded regarding pregnancy induced hypertension, gestational diabetes mellitus , anemia, antepartum hemorrhage, obstetric shock and intrapartum hemorrhage Maternal outcomes will be recorded regarding mode of delivery ,time of delivery ,preterm labor ,obstructed labor and prolonged labor Fetal outcomes will be recorded regarding congenital malformation ,intra uterine growth retardation ,intra uterine fetal death and still birth Perinatal outcomes will be recorded regarded birth weight ,birth asphyxia , neonatal hypoglycemia ,hyperbilirubinemia and ICU admission
Study Type
OBSERVATIONAL
Enrollment
100
Mansoura university hospital
Al Mansurah, Egypt
Comparing the Obstetric outcomes as Gestational diabetes mellitus between the young and the elderly group
Gestational diabetes mellitus by using oral glucose tolerance test between 24 : 28 weeks of pregnancy (in mg/dl),
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Obstetric outcomes as Anemia between the young and the elderly group
Detecting Anemia by measuring hemoglobin level (in gm/dl).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Obstetric outcomes as Oligohydramnios or polyhydramnios between the young and the elderly group
Detected by measuring (amniotic fluid index in cm) by ultrasound.
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Maternal outcomes as Preterm labor between the young and the elderly group
Preterm labor before 37 w of pregnancy calculated from last menstrual period.
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Fetal outcomes of pregnancy between the young and the elderly group
Fetal outcomes include: \- Congenital malformation \& Intra uterine fetal death (detected by anomaly scan).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Perinatal outcomes as Birth weight between the young and the elderly group
Birth weight (in gm).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Neonatal hypoglycemia between the young and the elderly group
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Detected by measuring neonatal blood glucose level (mg/dl).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Neonatal outcomes of pregnancy between the young and the elderly group
Include: * APGAR score system. * Neonatal intensive care unit admission
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Obstetric outcomes as Gestational diabetes mellitus between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Gestational diabetes mellitus by using oral glucose tolerance test between 24 : 28 weeks of pregnancy (in mg/dl),
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Obstetric outcomes as Anemia between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Detected by measuring hemoglobin level (in gm/dl).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Obstetric outcomes as Oligohydramnios or polyhydramnios between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Oligohydramnios or polyhydramnios by measuring (amniotic fluid index in cm) by ultrasound.
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Maternal outcomes of pregnancy between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Preterm labor before 37 w of pregnancy calculated from last menstrual period.
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Fetal outcomes of pregnancy between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Congenital malformation \& Intra uterine fetal death (detected by anomaly scan).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Perinatal outcomes as Birth weight between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Birth weight (in gm).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Neonatal hypoglycemia of pregnancy between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Neonatal hypoglycemia by measure neonatal blood glucose level (mg/dl).
Time frame: Between June 2021 to June 2022 and may be extended if needed
Comparing the Neonatal outcomes of pregnancy between women with spontaneous pregnancy and those using Assisted Reproductive Technique
Include: * APGAR score system. * Neonatal intensive care unit admission
Time frame: Between June 2021 to June 2022 and may be extended if needed