Stellate Block Versus Nimodipine Infusion for Traumatic Brain Injury

Early Phase 1UnknownNCT05182619

Sohag University60 enrolled

Overview

the study is designed to perform an intervention for enhancement of cerebral blood flow in patients with traumatic brain injury showing vasospasm through transcranial doppler

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Traumatic Brain Injury

Interventions

ultrasound-guided stellate ganglion blockPROCEDURE

under aseptic conditions, using the ultrasound guidance, bilateral stellate ganglion block will be done using bupivacaine and betamethasone mixture, 8 ml volume will be given for each side

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients more than 18 ys old with isolated head trauma and traumatic brain injury Exclusion Criteria: * • Hemodynamic instability (mean ABP less than 70 mmHg) * History of severe systemic disease including cardiopulmonary failure or hepatorenal failure * Allergy to local anesthetics * Coagulation disorders * Abnormal neck structures disturbing normal anatomy as neck tumors

Outcomes

Primary Outcomes

enhancement of cerebral blood flow

increased blood flow through middle cerebral artery and basilar artery measured by transcranial doppler ultraound

Time frame: one week

Data from ClinicalTrials.gov

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