This study investigates under controlled conditions the variation of poorly ventilated lung units (silent spaces) in obese patients scheduled for laparoscopic bariatric surgery in the perioperative phase.
Eligible patients with written informed consent, scheduled for laparoscopic bariatric surgery. As for standard of care no premedication will be given for bariatric patients. Patients will be monitored according the local standard. Thoracic electrical impedance tomography measurements (each measurement will last 1 min) will be performed at the following time points: before induction of the anaesthesia; before the surgical procedure when the induction is terminated and recruitment manoeuvers have been performed; after the termination of the surgical procedure; before transport to the Post anaesthesia Care Unit (PACU); before the discharge from the PACU after 2 hours of monitoring. An additional thoracic electrical impedance tomography measurement (duration 1 min) will be performed before discharge at home. For this, resulting potential differences are measured, and impedance distribution sampled at 30 Hz will be calculated by an automated linearized Newton-Raphson reconstruction algorithm. Relative change in poorly ventilated lung regions (silent spaces) and end-expiratory lung impedance (EELI) and measures of ventilation inhomogeneity such as the global inhomogeneity index will be calculated.
Study Type
OBSERVATIONAL
Enrollment
30
Thoracic electrical impedance tomography measurements ( min each) will be performed at the following time points: before induction of the anaesthesia; before the surgical procedure when the induction is terminated and recruitment manoeuvers have been performed; after the termination of the surgical procedure; before transport to the Post anaesthesia Care Unit (PACU); before the discharge from the PACU after 2 hours of monitoring. An additional thoracic EIT-measurement will be performed before discharge at home. For this, resulting potential differences are measured, and impedance distribution sampled at 30 Hz will be calculated. Relative change in poorly ventilated lung regions (silent spaces) and end-expiratory lung impedance (EELI) and measures of ventilation inhomogeneity will be calculated using customised code (Matlab R2021a, The MathWorks, Nattick, Massachusetts, USA).
University Hospital Bern
Bern, Switzerland
Proportion of poorly ventilated lung areas (silent spaces)
Proportion of poorly ventilated lung areas (silent spaces) by using electrical impedance tomography (EIT) before the discharge from PACU (two hours after admission to PACU).
Time frame: 2 hours
EIT-Measurement after the end of induction before the surgical procedure
Detection of changes in silent spaces, ventilation inhomogeneity and end-expiratory lung impedance (EELI) by using electrical impedance tomography (EIT)
Time frame: 2 minutes after the end of anesthesia induction
EIT-Measurement at the end of the surgical procedure
Detection of changes in silent spaces, ventilation inhomogeneity and end-expiratory lung impedance (EELI) by using electrical impedance tomography (EIT)
Time frame: 5 minutes after Capnoperitoneum
EIT-Measurement 2 minutes after the end of anaesthesia, before the transport in PACU
Detection of changes in silent spaces, ventilation inhomogeneity and end-expiratory lung impedance (EELI) by using electrical impedance tomography (EIT)
Time frame: 2 minutes after the end of anaesthesia, before the transport to PACU.
EIT-Measurement before discharge from the PACU
Detection of changes in silent spaces, ventilation inhomogeneity and end-expiratory lung impedance (EELI) by using electrical impedance tomography (EIT)
Time frame: Two hours after admission of the patient at PACU, before first mobilisation and before discharge from PACU
EIT-Measurement before discharging the patient at home
Detection of changes in silent spaces, ventilation inhomogeneity and end-expiratory lung impedance (EELI) by using electrical impedance tomography (EIT)
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Time frame: At hospital discharge, up to 3 days
Duration of surgical procedure.
Duration of surgical procedure.
Time frame: Up to 90 to 150 minutes
Duration of anaesthesia
Duration of anaesthesia
Time frame: Up to 90 to 180 minutes
Desaturation below 90%.
Difference of formation and course of silent lung areas in patients with and without pre-existing CPAP-therapy
Time frame: During anaesthesia monitoring, from 1 to 10 minutes
Follow up at 14 days
Follow-up by phone, regarding respiratory complications or need for rehospitalization.
Time frame: 14 days