Hemodynamic Optimization Based on a Dynamic Elastance Protocol

Fondazione Policlinico Universitario Agostino Gemelli IRCCS46 enrolled

Overview

In this study investigators explore the effects of a dynamic elastance guided protocol compared to a stroke volume variation fluid therapy on lactate levels during major abdominal surgery. Hence investigators created two groups: in the intervention group fluids are given in fluid-responders (SVV \> 13%) based on high value of dynamic elastance (ie. Eadyn \> 0.9). In the standard group fluids are administered when SVV \> 13%.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Fluid Management

Interventions

Elastance GroupBEHAVIORAL

Fluids are given based on dynamic elastane value

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: patients enrolled for major abdominal surgery \- Exclusion Criteria: 1. end-stage renal disease 2. severe heart dysfunction 3. heart rhythm alterations

Locations (1)

Andrea Russo

Rome, Italy

Outcomes

Primary Outcomes

lactate levels

Time frame: at the end of surgery

Data from ClinicalTrials.gov

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