Over the last decade, e-cigarettes have become increasingly popular, due to their promotion as a healthy alternative to traditional tobacco cigarettes. However, there are large discrepancies of knowledge in understanding how these e-cigarettes affect the user's health. The overall goal of this study is to evaluate the impact of e-cigarettes usage on user's cardiopulmonary health
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
4
A commercially available cartridge-based device with tobacco flavored liquid.
A commercially available cartridge-based device with tobacco flavored liquid.
Virginia Commonwealth University
Richmond, Virginia, United States
Change in Peak oxygen consumption (VO2 peak)
Participants' peak oxygen consumption (VO2 peak) will be measured using a standardized exercise capacity test performed on a stationary bike.
Time frame: Change from baseline to 2 weeks
Change in Expiratory Volume
Participants expiratory volume will be measured through spirometry using a pulmonary function device.
Time frame: Change from baseline to 2 weeks
Change in Skeletal muscle O2 utilization
Assessment of skeletal muscle oxygen utilization using near-infrared spectroscopy through the ratio of O2 delivery and O2 extraction
Time frame: Change from baseline to 2 weeks
Change in Maximal microvascular dilation
Participants' microvascular function (maximal dilation) will be measured using local thermal hyperemia.
Time frame: Change from baseline to 2 weeks
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