1-standardization of semi quantitative muscle ultrasonographic parameters ( muscle thickness (MT) and echo intensity (EI) ) in healthy adults and to obtain a set of normal values of all accessible muscle in both upper and lower limbs. 2.standardizaition of quantitative muscle ultrasonographic parameters (Gray scale level (GSL), Calibrated muscle backscatter values (cMBs), Optical Density (OD), 2D Textu1) in healthy adults and to obtain a set of normal values of all accessible muscle in both upper and lower limbs.
. Ultrasound is a widely used imaging technique in many different medical specialties. It is a non-invasive, safe and relatively cheap investigation method. Ultrasound is a non-invasive method to quantitatively measure various muscle parameters. Ultrasound imaging (US) has shown to be capable of visualizing normal and pathological skeletal muscles.(1) By measuring muscle thickness (MT) and echo intensity (EI) (=grey-value) of the muscle, structural changes caused by neuromuscular disorders can be detected. (2, 3, 4) Quantitative evaluation of US images is preferable over visual evaluation, because it is more sensitive and objective and offers the possibility to perform statistical analysis.(5) A prerequisite for the diagnostic use of quantitative muscle US is the availability of normal reference values. Ultrasonography can detect structural muscle changes caused by neuromuscular disease. Quantitative analysis is the preferred method to determine if ultrasound findings are within normal limits, but normative data are incomplete.(6)
Study Type
OBSERVATIONAL
Enrollment
100
All subjects will undergo the tests with the same machine. Transverse ultrasound images were obtained using the Philips HD with a 4-12 MHz probe. in neurosonology unit in neurology department.
get a refrence for ultrasonographic parameters muscle
1. use new, easy ,non-invasive tool "neuromuscular ultrasound" 2. ultrasound give important morphological information of the muscles and can differentiate normal and diseased muscle. 1\_use new, easy ,non-invasive tool "neuromuscular ultrasound" 2\_ultrasound give important morphological information of the muscles and can differentiate normal and diseased muscle.1\_use new, easy ,non-invasive tool "neuromuscular ultrasound" 2\_ultrasound give important morphological information of the muscles and can differentiate normal and diseased muscle.
Time frame: 10 months
detect early pathological changes in muscles
Ultrasonography give pathophysiological insights and substantially added to diagnostic accuracy and treatment decisions amongst myopathies
Time frame: 8 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.