Acute myocardial infarction (AMI) is one of the leading causes of death around the world, with the potential for substantial morbidity and mortality. The increasing evidence indicates that exercise training has beneficial effects on LV remodelling in post-MI patients with greater benefits occurring when training earlier following MI, among which the earliest time for rehabilitation is one week after myocardial infarction. However, the effect of Baduanjin sequential therapy for patients after one week of AMI has yet to be assessed. Therefore, the aim of this study is to assess the impact of Baduanjin sequential therapy on cardiac and physical function in patients with AMI and reduced ejection fraction after primary PCI.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
140
A detailed description of a standardized Baduanjin exercise protocol complied with the "Health Qigong Baduanjin Standard" enacted by the General Administration of Sports in 2003.
Participants allocated to the usual exercise control group receive a closely supervised, group-format aerobic exercise program located at home or cardiac rehabilitation centre lasting 3 months. The program is consistent with the current recommended guidelines of moderate-intensity exercises for MI.
General Hospital of Shenyang Military Region
Shenyang, Liaoning, China
RECRUITINGLeft ventricular ejection fraction (LVEF)
The change in echocardiographic measures of left ventricular ejection fraction，(LVEF). LVEF in %.
Time frame: baseline and 3 months
SF-36
the SF-36 has 36 items grouped in 8 dimensions: physical functoning, physicial and emotional limitations, social functioning, bodily pain, general and mental health.
Time frame: baseline and 3 months
Generalized Anxiety Disorder 7-item (GAD-7)
The Generalized Anxiety Disorder 7 (GAD-7) is a 7-item instrument used to briefly measure or assess one of the most common mental disorders.
Time frame: baseline and 3 months
Patient Health Questionnaire (PHQ-9)
The PHQ-9 is the depression module, which scores each of the nine DSM-IV criteria as "0" (not at all) to "3" (nearly every day). It has been validated for use in primary care. It is not a screening tool for depression but it is used to monitor the severity of depression and response to treatment.
Time frame: baseline and 3 months
Seattle Angina Questionnaire (SAQ)
The Seattle Angina Questionnaire (SAQ), developed by Spertus and first reported in the literature in 1994, increasingly is being used to measure cardiac disease-specific quality of life in patients with CAD and
Time frame: baseline and 3 months
Minnesota Satisfaction Questionnaire (MSQ)
The Minnesota Satisfaction Questionnaire (MSQ) is initially designed to measure an employee's satisfaction with his or her job.
Time frame: baseline and 3 months
Traditional Chinese Medicine (TCM) symptom score scale
Traditional Chinese Medicine (TCM) symptom score scale is a score scale for evaluating patients' symptoms from the perspective of TCM. The full score is 30 points, 7-14 points are mild, 15-22 points are moderate and ≥23 points are severe.
Time frame: baseline and 3 months
CPET operators-Peak VO2/kg
Cardiopulmonary exercise testing ( CPET) is one kind of integrative evaluation of the subject's cardiopulmonary function under a certain exercise load. The information gathered during a CPET is used to calculate Peak VO2 (the highest level of oxygen consumption attained at peak exercise). (ml/kg/min)
Time frame: baseline and 3 months
CPET operators-metabolic equivalent (METs)
In cardiology, and especially when treadmill protocols are used, it is common to express the metabolic requirement for external work as the metabolic equivalent (MET). "MET" is defined as the equivalent of the resting metabolic oxygen requirement. One metabolic equivalent equals 3.5 ml/kg per minute. Exercise capacity (in METS) is a powerful predictor of mortality among men referred for exercise testing. (unit in METs)
Time frame: baseline and 3 months
CPET operators-peak O2-pulse
Another value calculated by CPET is the peak O2-pulse, which indicates how much blood one's heart can pump out with each beat (at the peak level of exercise). (ml/beat)
Time frame: baseline and 3 months
6-minute walk distance (6MWD)
A 6-minute walk test measures the distance patients can quickly walk in 6 minutes. (in meters)
Time frame: baseline and 3 months
Exercise compliance-exercise time
Exercise time. (in minutes)
Time frame: baseline and 3 months
Exercise compliance-Exercise frequency
Exercise frequency. (per week)
Time frame: baseline and 3 months
N-terminal pro-brain natriuretic peptide (NT-pro BNP)
N-terminal pro-brain natriuretic peptide (NT-pro BNP) in pg/ml
Time frame: baseline and 3 months
LV end-diastolic volume (LVEDV)
The change in echocardiographic measures of ventricular volumes (LV end-diastolic volume). LVEDV in ml.
Time frame: baseline and 3 months
LV end-systolic volume (LVESV)
The change in echocardiographic measures of ventricular volumes (LV end-systolic volume). LVESV in ml.
Time frame: baseline and 3 months
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