Use of Testicular Spermatozoa in Non-azoospermic Patients

N/AUnknownNCT05203211

Istituto Clinico Humanitas120 enrolled

Overview

Use of testicular spermatozoa in non-azoospermic patients.

The aim of the study is to evaluate the characteristics of couples whose male partner is offered TESE after the failure of previous ICSI technique performed with ejaculated semen. All couples in a third-level University affiliated centre, between January 2010 and January 2020, whose male partner were diagnosed with any type of oligospermia and underwent TESE after ICSI from ejaculated semen, were included in the analysis.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Male Infertility

Interventions

Testicular sperm extraction (TESE)PROCEDURE

During the procedure, the testis is exposed through a small incision and one or more biopsies are taken blindly. A vertical incision is made in the median raphe, skin, dartos and tunica vaginalis to expose tunica albuginea. The tunica albuginea is incised for about 4 mm at upper pole near the head of epididymis.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients undergone testiscular sperm extraction (TESE) after failure of ICSI with the use of ejaculated sperm Exclusion Criteria: * Female age \>40 yo

Locations (1)

Istituto Clinico Humanitas

Rozzano, Milano, Italy

RECRUITING

Outcomes

Primary Outcomes

fertilization rate (FR)

Evaluate if there is a higher fertilization rate in male patients undergone TESE

Time frame: 10 years

Secondary Outcomes

Blastulation rate (BR)

Evaluate if there is a higher blastulation rate in male patients undergone TESE

Time frame: 10 years

Miscarriage rate (MR)

Evaluate if there is a lower miscarriage rate in male patients undergone TESE

Time frame: 10 years

Data from ClinicalTrials.gov

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