Telehealth Exercise Intervention to Improve Cardiovascular Health in Lymphoma Survivors, TECHS Trial

N/ACompletedNCT05205512

City of Hope Medical Center10 enrolled

Overview

This clinical trial tests how well a telehealth exercise intervention works to improve cardiovascular health in lymphoma survivors. Telehealth exercise is a service to help perform physical exercises at home with a care provider online. With the use of telehealth exercise lymphoma survivors may be able to participate in exercise programs safely to improve heart health and reduce the risk of cardiovascular disease.

PRIMARY OBJECTIVE: I. Determine the feasibility of an 8-week telehealth exercise intervention, as assessed by enrollment, retention, and adherence to the telehealth exercise intervention. SECONDARY OBJECTIVE: I. Explore the effects of an 8-week telehealth exercise intervention on cardiovascular health, assessed by cardiopulmonary exercise test, pulmonary function test, body compositions, and blood biomarkers. OUTLINE: Participants are randomized into 1 of 2 groups. GROUP I (TELEHEALTH EXERCISE): Patients participate in telehealth exercise intervention for 30 minutes per day, 3 days a week for 8 weeks. GROUP II (DELAYED CONTROL): Patients maintain current levels of physical activity for 8 weeks. Patients may then participate in telehealth exercise intervention for 8 weeks. After completion of study treatment, participants are followed up after 1 week.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Hodgkin Lymphoma Non-Hodgkin Lymphoma

Interventions

Exercise InterventionOTHER

Maintain current levels of physical activity

Questionnaire AdministrationOTHER

Ancillary studies

TelemedicineOTHER

Participate in telehealth exercise intervention

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with Hodgkin or non-Hodgkin lymphoma. * \>= 18 years old. * Are between 2-5 years after completing anti-cancer therapy and with no evidence of disease. * Intermediate (4-5) to high ( \>= 6) risk of cardiovascular risk factors based on six key variables: Age 30 to 50 years (y) \[2\]) and \>= 50y \[3\]; anthracycline dose \>250mg/m \^ 2 \[1\]; hypertension \[2\]; diabetes \[2\]; smoking \[1\]; and chest radiation \[1\]). * Able to understand and sign the informed consent document. * Physically able and willing to complete all study procedures. Exclusion Criteria: * Have overt cardiovascular disease within 6 months (e.g. myocardial infarction, stroke, angina). * Have contraindications to exercise. * Participate in structured exercise (\>60 minutes/week). * Female patients who are pregnant or planning to become pregnant.

Locations (1)

City of Hope Medical Center

Duarte, California, United States

Outcomes

Primary Outcomes

Adherence to the telehealth exercise intervention

Adherence will be measured by the number of exercise sessions attended over the exercise sessions prescribed (17/24 sessions).

Time frame: Up to 2 years

Secondary Outcomes

Effects of an 8-week telehealth exercise intervention

The physiologic effects of telehealth exercise intervention will be assessed by peak oxygen consumption (VO2) using cardiopulmonary exercise testing.

Time frame: At baseline up to week 9

Data from ClinicalTrials.gov

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