Cryptosporidium species are increasingly recognized as important enteric pathogens that infect a broad range of hosts including human, domestic and wild animals worldwide, causing asymptomatic or mild-to-severe gastrointestinal disease in their host species. There are 38 species of Cryptosporidium that have been described, going from amphibian parasites to mammals ones, with over 40 genotypes infecting mammals, although Cryptosporidium parvum and Cryptosporidium hominis are the two species predominantly reported in human infections. In Cairo and Sharkyia governorates in Egypt, Cryptosporidium is a common intestinal parasite among children, especially in diarrheic, preschool-aged children, with a predominance of C. hominis indicates anthroponotic rather than zoonotic transmission. Also in the sohag governorate, Cryptosporidium infection is a common intestinal parasite, as in the last five years its prevalence about 35% but there is no study clarify predominant genotype of Cryptosporidium in sohag.
Study Type
OBSERVATIONAL
Enrollment
200
Faculty of Medicine, Sohag University
Sohag, Egypt
RECRUITINGestimate the prevalence and clarify the species and genotypes/subtypes of Cryptosporidium spp. in sohag.
Time frame: 24 weeks
clarify the relationship of them in a phylogenetic context and to provide additional information on the molecular epidemiology of this parasite in our locality
Time frame: 24 weeks
clarify the predominant clinical manifestation of each genotypes/subtypes of Cryptosporidium spp
Time frame: 24 weeks
clarify the relationship between genotypes/subtypes of Cryptosporidium spp. and different risk factors.
Time frame: 24 weeks
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