Myocardial stunning during chronic intermittent hemodialysis is a well-described phenomenon. Little case series of patients presenting myocardial stunning during renal replacement therapy for acute kidney injury in critically ill patients are reported, with intermittent hemodialysis and continuous renal replacement therapy. However, the small sample sizes and the absence of a control arm limit their interpretation, mainly whether the myocardial stunning may be related to cardiac loading conditions variations and whether it may impact the hemodynamic. The investigator hypothesize that myocardial stunning induced by renal replacement therapy is frequent, independent from cardiac loading conditions and associated with peripheral hypoperfusion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
42
Continuous renal replacement therapy (veno venous hemofiltration) without net ultrafiltration, through a dedicated central venous catheter
Continuous renal replacement therapy is differed from 6 hours to allowed 2 control echocardiographic evaluations
Département d'anesthésie-réanimation Hôpital cardiologique Louis Pradel Groupe Hospitalier Est
Bron, Bron, France
Ruste Martin
Bron, BRON, France
Hopital Edourd Herriot
Lyon, France
Number of segment of the left ventricle with regional wall motion abnormalities
Numbers of segments of the left ventricle (by patient) with a decrease greater than 20% of the peak systolic longitudinal strain (2D speckle tracking) on the second echocardiography as compared to baseline.
Time frame: Change between the echocardiography at baseline and the echocardiography 4 hours after.
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