Randomized, double-blind clinical trial to compare the efficacy of catheter sealing with saline, compared to low-dose heparin. 3,450 patients hospitalized at the Hospital Residencia Sant Camil, in Catalonia (Spain), will be randomized to each branch of study. The primary outcome will be the percentage of catheters removed due to obstruction in each branch of study. As secondary outcomes, the number of catheter-associated phlebitis, catheter-associated bacetrihemia, extravasation, and catheter loss will be measured. For the primary outcome, a superiority analysis will be carried out in terms of the percentage of obstructed catheters in each branch of the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Enrollment
3,450
Catheters will be sealed with 3 mL of Fibrillin Ⓡ (heparin 20UI/mL)
Catheters will be sealed with 3mL of 0.9% sodium chloride
Hospital Residència Sant Camil
Sant Pere de Ribes, Barcelona, Spain
RECRUITINGPercentage of obstructed catheters
percentage of obstructed catheters
Time frame: From date of randomization through the date of hospital discharge, an average of 10 days.
Number of catheter-associated phlebitis
Number of catheter-associated phlebitis
Time frame: From date of randomization through the date of hospital discharge, an average of 10 days.
Number of catheter-associated bacterihemia episodes
Number of catheter-associated bacterihemia episodes
Time frame: From date of randomization through the date of hospital discharge, an average of 10 days.
Number of catheter loss due to extravasation
Number of catheter loss due to extravasation
Time frame: From date of randomization through the date of hospital discharge, an average of 10 days.
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