Single-cell CBD Biomarkers of Inflammation Reduction in People Living With HIV

Inclusion Criteria: * Willingness to take CBD and to participate in follow up for two months * Older than 21 and younger than 60 * Under antiretroviral therapy for 5+ years and suppressed viral load (CD4 count \<350cells/ml) Exclusion Criteria: * Conditions/medications that may impair the immune response, e.g., rheumatoid arthritis, cancer, diabetes, chronic infections, CAD (Cold agglutinin disease), cellulitis, autoimmune diseases such as lupus, sarcoidosis * All medications that may affect inflammation such as aspirin, steroids, statins; CD4 count \<350cells/ml), pregnancy, and current marijuana or CBD use (urine drug screen) * UF(University of Florida)/Shands staff and students will not be considered for enrollment