Since December 2019, more and more cases of unexplained pneumonia appeared after exposure to the South China Seafood Market in Wuhan City, Hubei Province. Later, the disease were confirmed to be acute respiratory infectious diseases caused by the 2019 new coronavirus infection. Even though we have had great victories in the war against this pandemic, there is still a very large number of deaths early on. As research progresses, vaccines for this infectious disease are already being developed. There are currently two vaccines in widespread use worldwide: mRNA vaccines and inactivated vaccines. In China, inactivated vaccines are more commonly used. At present, some studies believe that mRNA vaccine does not affect the pregnancy rate and abortion rate of women, but the study sample size is small, and the conclusions are limited. The effects of inactivated vaccines on fertility are still in the blank. We now hope to conduct prospective studies, mainly to study the effect of inactivated vaccine injection on male semen, and whether it has an effect on the quality of embryos in IVF patients
Study Type
OBSERVATIONAL
Enrollment
100
the vaccinated :Male patients who received more than 2 injections of the covid-19 vaccine;the unvaccinated :Male patients who did not receive the covid-19 vaccine
Shanghai First Maternity and Infant Health Hospital
Shanghai, China
RECRUITINGsemen index
the semen index of the participants
Time frame: 2022.01-2022.03
Fertilization rate
The percentage of eggs fertilized
Time frame: 2022.01-2022.04
embryo quality
Grading of formed embryos
Time frame: 2022.02-2022.05
clinical pregnant rate
after the embryo transplantation, calculate the pregnancy rate
Time frame: 2022.03-2022.05
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