Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football

N/ACompletedNCT05220969

St Mary's University College95 enrolled

Overview

A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury. This score was then compared with the incidence of injury between those with high, medium and low risk scores for each injury. The influence of different rates of growth, stages of physical maturation and loading exposure were then also included in the risk model to see if any interaction effects could be observed between genetic risk score and susceptibility to injury in different categories of growth, maturation and loading exposure.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Fractures in Children Apophysitis Muscle Strain Ligament Injury Tendon Injuries Genetic Predisposition

Interventions

Total Genotype Risk ScoreGENETIC

A total genotype risk score has been generated based on the results of previously observed genetic association studies

Eligibility

Sex: MALEMin age: 12 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Elite male football players Exclusion Criteria: * Female * non-elite

Locations (2)

Fulham Football Club

London, New Malden, United Kingdom

St Mary's University, Twickenham

London, Twickenham, United Kingdom

Outcomes

Primary Outcomes

Fracture Injury Risk

Did the risk of fracture differ between total genotype risk score categories? was this affected by maturation?

Time frame: 8 Years

Non-Contact Injury Risk

Did the risk of non-contact injury differ between total genotype risk score categories? was this affected by maturation, and loading?

Time frame: 8 Years

Non-Contact Muscle Injury Risk

Did the risk of non-contact muscle injury differ between total genotype risk score categories? was this affected by maturation, and loading?

Time frame: 8 Years

Tendon Injury Risk

Did the risk of tendon injury differ between total genotype risk score categories? was this affected by maturation, and loading?

Time frame: 8 Years

Ligament Injury Risk

Did the risk of ligament injury differ between total genotype risk score categories? was this affected by maturation?

Time frame: 8 Years

Apophysitis Injury Risk

Did the risk of ligament injury differ between total genotype risk score categories? was this affected by maturation?

Time frame: 8 Years

Data from ClinicalTrials.gov

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