Home Monitoring of Diabetic Macular Edema

Inclusion Criteria: 1. Age ≥18 years; 2. Diagnosis of diabetic macular edema: * Type 1 or type 2 diabetes mellitus; * Center-involved macular edema; 3. Willing to receive anti-VEGF treatment; 4. Media clarity, pupillary dilation, and individual cooperation sufficient for adequate OCT examination; 5. Able to operate self-administratedhome OCT by themselves or with the help of family; 6. Travel time from home to hospital: within 2 hours driving. 7. Able and willing to provide informed consent. Exclusion Criteria: 1. History of systemic anti-VEGF or pro-VEGF treatment within 4 months prior to randomization. (These drugs should not be used during the study); 2. History of corticosteroid treatment (intravitreal or peribulbar) at any time in the past 4 months; 3. History of macular laser photocoagulation in the past 4 months; 4. Macular edema due to reasons other than diabetes; 5. Coexisting ocular diseases that might alter visual acuity during the course of the study, such as retinal vein or artery occlusion, uveitis or other ocular inflammatory disease, neovascular glaucoma, etc.); 6. Hypertension (systolic blood pressure (BP) above 180 or diastolic BP above 110); 7. History of myocardial infarction, other acute cardiac event requiring hospitalization, stroke, transient ischemic attack, or treatment for acute congestive heart failure within 4 months prior to randomization; 8. Pregnant or lactating; 9. Currently participating in other clinical trials;