The primary aim of this study is to compare the effects of sevoflurane and desflurane on the QT interval. The secondary aim of this study is to compare the effects of drugs used in the induction and maintenance of anesthesia on the QT interval by calculating the Bazzet formula and iCEB.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Enrollment
120
6 precordial and 4 extremity electrodes will be placed at appropriate anatomical points and a total of 6 12-lead ECGs will be taken at different anesthesia depths before anesthesia induction and throughout the operation.
QTc T0
QTc; It is calculated by dividing the QT interval by the square root of the RR interval (QTc= QT/ √RR).
Time frame: Baseline, preoperative
QTc T1
QTc; It is calculated by dividing the QT interval by the square root of the RR interval (QTc= QT/ √RR).
Time frame: During surgery (at the time of the anesthesia induction)
QTc T2
QTc; It is calculated by dividing the QT interval by the square root of the RR interval (QTc= QT/ √RR).When the mac value reaches 0,6, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reached 0,6)
QTc T3
QTc; It is calculated by dividing the QT interval by the square root of the RR interval (QTc= QT/ √RR).When the mac value reaches 1, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reached1)
QTc T4
QTc; It is calculated by dividing the QT interval by the square root of the RR interval (QTc= QT/ √RR).When the mac value reaches 1,3 , it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reached 1,3)
QTc T5
QTc; It is calculated by dividing the QT interval by the square root of the RR interval (QTc= QT/ √RR).When the mac value reduces 0,3, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reduced 0,3)
iCEB T0
Index of cardio-electrophysiological balance (iCEB); calculated as QT distance divided by QRS duration (QT/ QRS)
Time frame: Baseline, preoperative
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iCEB T1
Index of cardio-electrophysiological balance (iCEB); calculated as QT distance divided by QRS duration (QT/ QRS)
Time frame: During surgery (at the time of the anesthesia induction)
iCEB T2
Index of cardio-electrophysiological balance (iCEB); calculated as QT distance divided by QRS duration (QT/ QRS) the mac value reaches 0,6, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reached 0,6)
iCEB T3
Index of cardio-electrophysiological balance (iCEB); calculated as QT distance divided by QRS duration (QT/ QRS) the mac value reaches 1, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reached 1)
iCEB T4
Index of cardio-electrophysiological balance (iCEB); calculated as QT distance divided by QRS duration (QT/ QRS) the mac value reaches 1,3, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reached 1,3)
iCEB T5
Index of cardio-electrophysiological balance (iCEB); calculated as QT distance divided by QRS duration (QT/ QRS) when the mac value reduces 0,3, it will be calculated from the ECG.
Time frame: During surgery (at the time of MAC reduced 0,3)