Diet can alter blood ketone levels and this in turn may affect exercise capacity. This study will determine if the acute ingestion of a ketone supplement alters cycling time trial performance. Participants will perform two trials in a randomized order. Each trial will involve a 20-minute bout of cycling on a stationary ergometer. Participants will ingest either a ketone supplement or a taste-matched placebo drink prior to exercise. Blood samples will be obtained to assess selected metabolic responses. This study will provide information regarding the effect of ketone supplementation on exercise responses.
This study will determine if the acute ingestion of a ketone supplement alters cycling time trial performance. Trained participants with competitive cycling experience will be recruited. Exercise will involve a 20-minute bout of cycling on a stationary ergometer with the goal of producing the highest power output possible. Participants will ingest either a ketone supplement or a taste-matched placebo drink prior to exercise using a randomized, double-blind crossover design. Diet prior to exercise will be standardized between trials for a given participant. Blood samples will be obtained to assess selected metabolic responses. This study will provide information regarding the effect of ketone supplementation on exercise responses.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
25
A commercial liquid supplement ingested in a dose intended to provide \~0.35 g of ketone monoester per kg body mass of the participant
A liquid placebo that is volume- and taste-matched to the ketone monoester supplement
McMaster University
Hamilton, Ontario, Canada
Power output
Mean power output produced while cycling
Time frame: 20-minute measurement during exercise
Heart rate
Mean heart rate while cycling
Time frame: 20-minute measurement during exercise
Perceived exertion
Rating of perceived exertion while cycling
Time frame: Single measurement immediately after exercise
Blood ketone
Blood ketone before exercise
Time frame: Single measurement immediately prior to exercise
Blood glucose
Mean blood glucose while cycling
Time frame: 20-minute measurement during exercise
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