Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty

Survivorship of all individual SYMBOL orthopaedic components

The survival rate of an orthopaedic implant will be calculated on the basis of the first occurrence of implant revision from any cause.

Time frame: 6 months, 18 months and 5 years post-operative

Survivorship of the SYMBOL STEM VARA CEM orthopaedic implant.

The survival rate of an orthopaedic implant will be calculated on the basis of the first occurrence of implant revision from any cause.

Time frame: 10 years post-operative

Survivorship of the SYMBOL implants by component assembly (acetabular + femoral components)

The survival rate of a combinaison of implant (acetabular + femoral component) will be calculated on the basis of the first occurrence of implant revision from any cause.

Time frame: Through study completion, an average of 10 years

Adverse Device Effects.

All adverse device effects occurring from the time of subject enrollment until study termination or study completion including intra-operative adverse events. Note: This outcome will also be used for subgroup analyses by component association.

Time frame: Through study completion, an average of 10 years

Radiographic assessment - Implant subsidence.

Stem subsidence will be classified based on the following: * Stem subsidence \< 3mm * Stem subsidence between 3 and 5mm * Stem subsidence \> 5mm Note: This outcome will also be used for subgroup analyses by component association.

Time frame: 6 months, 18 months, 5 and 10 years post-operative

Radiographic assessment - Osteolysis (granuloma).

Assessment will consider: \- Presence or absence of osteolysis. If osteolysis is present, impacted areas will be determined according to DeLee and Charnley or Gruen classification. Note: This outcome will also be used for subgroup analyses by component association.

Time frame: 6 months, 18 months, 5 and 10 years post-operative

Radiographic assessment - Radiolucent lines.

Assessment will consider: \- Presence or absence of radiolucent lines. If radiolucent line is present: * Impacted areas will be determined according to DeLee and Charnley or Gruen classification. * Type of radiolucent lines will be classified based on the following : \< 2mm - regular or \> 2mm - irregular. Note: This outcome will also be used for subgroup analyses by component association.

Time frame: 6 months, 18 months, 5 and 10 years post-operative

Radiographic assessment - Eterotopic ossifications.

Assessment will consider: \- Presence or absence of eterotopic ossifications. If eterotopic ossification, grade will be specified. This outcome will also be measured for subgroup analyses by component association.

Time frame: 6 months, 18 months, 5 and 10 years post-operative

Harris Hip Score (or modified Harris Hip Score) at each visit.

The Harris Hip Score is a joint specific score that consists of 10 items covering domains of pain, function, functional activities, absence of deformity, and hip range of motion. Note: This outcome will also be used for subgroup analyses by component association.

Time frame: Pre-operative, 6 months, 18 months, 5 and 10 years post-operative

Pain intensity (Numeric Rating Scale)

Numeric Rating scale for pain intensity assessment: * Minimum value: 0 (=no pain) * Maximum value: 10 (= worst possible pain). (Higher scores mean worst outcome). Note: This outcome will also be used for subgroup analyses by component association.

Time frame: Pre-operative, 6 months, 18 months, 5 and 10 years post-operative

EQ-5D-5L score

The EQ-5D-5L score consists of two parts: a descriptive system and a visual analogue scale. The descriptive system is used to describe the subject's health state and consists of five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. The visual analogue scale records the subject's self-rated health on a vertical visual analogue scale. Note: This outcome will also be used for subgroup analyses by component association.

Time frame: Pre-operative, 18 months, 5 and 10 years post-operative

Global patient satisfaction

Ordinal scale for global patient satisfaction assessment: \- Possible values are: not satisfied/quite satisfied/satisfied/very satisfied ("Very satisfied" is the best possible outcome).

Time frame: 18 months post-operative

Hip joint patient satisfaction (Numeric Rating Scale)

Numeric rating scale : Percentage Scale for Hip Joint Patient Satisfaction Assessment. Range of values: from 0 to 100. (100 is the best possible outcome and is equivalent to a normal hip). Note: This outcome will also be used for subgroup analyses by component association.

Time frame: 5 years and10 years post-operative