Comparison of the TOFScan and the WiTOF During Recovery of Neuromuscular Function

Poitiers University Hospital80 enrolled

Overview

The purpose of this study is to compare two neuromuscular blockade monitors on recovery from an ATRACURIUM intra veinous injection for surgery. The TOFscan, a wired connected monitors and the WiTOF, a wireless connected monitor.

The secondary objective will be to compare the performance of the two monitors on the abductor pollicis muscle with all the curarisation parameters (TOF, PTC, T4/T1R) and to assess interference occuring during the surgery which could limit the usage of a wireless monitor.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Neuromuscular Residual Curarization

Interventions

WiTOFDEVICE

Data collection on the WiTOF monitor

TOFscanDEVICE

Data collection on the TOFscan monitor

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All programmed surgery with intraveinous injection of ATRACURIUM * American society of anesthesiology patient score of I, II or III * Patient being free of tutorship or curatorship * Acceptance of the patient after clear and loyal information Exclusion Criteria: * Surgery without access simultaneously to the two arms * Emergency surgery * Rapid sequence induction * Usage of an other curare than ATRACURIUM * Contraindication on ATRACURIUM usage * Patient with pace maker * Patient with Arné score \> or = to 11 * Patient without social security coverage * Pregnant of breastfeeding women * Patient under social protection

Locations (1)

CHU de Poitiers

Poitiers, France

Outcomes

Primary Outcomes

Evaluate the neuromuscular blockade recovery after intraveinous injection of atracurium with 2 differents monitors.

Comparison on the obtention delay for the T4/T1 ratio superior ou equal to 90% beetween the WiTOF and the TOFScan

Time frame: During the whole period of the surgical operation maximum 8 hours

Secondary Outcomes

Evaluate the performance of the monitors for the follow up of neuromuscular recovery

Comparison of neuromuscular blockade parameters obtained with the WiTOF and the TOFScan (TOF, PTC, T4/1R)

Time frame: During the whole period of the surgical operation maximum 8 hours

Number and duration of perturbation from the surgical environnement that could limit the usage of a wireless monitor

Assess what could perturbate the data collection on the wireless monitor

Time frame: During the whole period of the surgical operation maximum 8 hours

Data from ClinicalTrials.gov

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