Cross-Over Study to Compare the Pharmacokinetics and Pharmacodynamics of LIB003 Process 1 and Process 2 Drug Product

Inclusion Criteria: * Provision of written and signed informed consent prior to any study-specific procedure * LDL-C 70 mg/dL or above on stable diet alone or diet plus statin * Weight of 40 kg (88 lb) and body mass index (BMI) between 17 and 42 kg/m2 * Females of childbearing potential must be using a highly effective form of birth control * Male subjects will either be surgically sterile or agree, or partner agrees, to use highly effective form of birth control Exclusion Criteria: * Fasting triglyceride \>400 mg/dL * excluded lipid lowering medication * severe renal impairment (eGFR \<30 ml/min) * fasting glucose \>200 mg/dL plus HbA1c \>9% * hepatic transaminases \>2.5 x ULN for laboratory * History of any prior or active clinical condition or acute and/or unstable systemic disease compromising subject inclusion, at the discretion of the Investigator, * NYHA class III-IV heart failure or last documented left ventricular EF \<30% * Any severe or clinically significant advert event, laboratory abnormality, intercurrent illness, or other medical condition which indicates to the Investigator that continued participation is not in the best interest of the subject