The Role of Interferon-gamma in Immune Responses to Invasive Candidiasis

Subjects must meet all following inclusion criteria to qualify for the study: 1. Willing and able to provide written informed consent. If the subject is unable to consent for himself/herself, a legally authorized representative must provide informed consent on his/her behalf. 2. Males or females ≥18 years of age 3. Patients having one or more systemic signs attributable to candidemia or invasive candidiasis (fever, hypothermia, hypotension, tachycardia, tachypnea, local signs of inflammation). 4. Isolation of Candida from blood, intra-abdominal abscess/peritoneal fluid or pleural fluid. Exclusion Criteria Subjects must NOT meet any of the following exclusion criteria to qualify for the study: 1. Severe neutropenia (absolute neutrophil count \<500 cells/microL) 2. Profound lymphopenia (\<300 cells/microL) 3. The Principal Investigator (PI) is of the opinion the subject should not participate in the study. 4. Females who are pregnant.