As part of this study, you may have a procedure called phototherapy which involves either VL-UVA or NB-UVB irradiation. NB-UVB phototherapy is not experimental in vitiligo, but use of VL-UVA1 phototherapy in vitiligo is. The purpose of this pilot study is to determine whether VL-UVA1 or NB-UVB phototherapy more efficiently induces repigmentation in patients with generalized vitiligo.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
1
Patients will have different kinds of light shined on different areas
Department of Dermatology, Henry Ford Medical Center, 3031 West Grand Boulevard,
Detroit, Michigan, United States
Change in depigmentation of vitiligo lesion
Change in pigment will be assessed by colorimetry which measures change in pigment
Time frame: 13 measurements over 26 visits
Change in melanin content of vitiligo lesion
Change in pigment will be assessed by diffuse reflectance spectroscopy which will measure the melanin content and dyschromia
Time frame: 13 measurements over 26 visits
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