Acute STROke Complicating TAVI - Management and Outcomes

Rabin Medical Center484 enrolled

Overview

Periprocedural complications of trans catheter aortic valve implantation, and particularly the occurrence of stroke has a marked impact on survival and quality of life. The characteristics of periprocedural stroke complicating TAVI, and particularly of interventions aimed to treat stroke complicating TAVI have not been systematically described. We therefore aimed is to explore the incidence and characteristics of acute stroke complicating TAVI and to describe the safety and efficacy of emergent interventions to treat acute stroke complicating TAVI.

Study Type

OBSERVATIONAL

Enrollment

484

Conditions

Stroke Aortic Valve Stenosis Periprocedural Complication

Interventions

Mechanical thrombectomyPROCEDURE

Percutaneous intervention aimed to retrieve/treat clot affecting the cerebral circulation.

Thrombolytic AgentDRUG

Drug aimed to dissolve thrombus affecting the cerebral circulation

Eligibility

Sex: ALLMin age: 18 YearsMax age: 120 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients who have had a stroke within 30 days of TAVI Exclusion Criteria: * none

Locations (1)

Rabin Medical Center

Petah Tikva, Israel

Outcomes

Primary Outcomes

All cause mortality

All cause death

Time frame: 1-year

Neurologic disability free survival

modified rankin score (mRS) 0/1

Time frame: 90 days

Secondary Outcomes

Bleeding complications

Severe bleeding / life-threatening bleeding as defined by VARC2 criteria

Time frame: 30 days

Data from ClinicalTrials.gov

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