Quadratus Lumborum Block for Total Hip Arthroplasty

Early Phase 1Enrolling By InvitationNCT05247255

University of California, Los Angeles80 enrolled

Overview

The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip arthroplasty (THA).

Investigators will enroll subjects planned for primary THA and allocate them into receiving a QL block with either saline or ropivacaine. Primary outcome will be pain scores over the first 48 hours after surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Pain, Postoperative

Interventions

Active ComparatorDRUG

QL block with 0.25% ropivacaine

Placebo ComparatorDRUG

QL block with saline

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult subjects undergoing elective primary total hip arthroplasty Exclusion Criteria: * patients age \< 18, * documented allergy to local anesthetic * presence of peripheral neuropathy * patients with current long term opioid use defined as receiving an opioid on most days in a 90 day period * patients with a contraindication to spinal and regional anesthesia such as coagulopathy or infection at the site of the regional technique.

Locations (1)

UCLA Medical Center, Santa Monica

Santa Monica, California, United States

Outcomes

Primary Outcomes

Pain score

Pain scores will be assessed over 48hrs postop using the visual analog score

Time frame: Up to 48 hrs post op

Secondary Outcomes

Opioid usage

Total morphine-equivalent will be calculated at 0-24hrs and 24-48hrs postop.

Time frame: Up to 48 hrs post op

Time to first stand

The period between the end of surgery and the patient's first successful attempt at standing, with or without the assistance of devices (i.e. walker, cane) or staff assistance.

Time frame: Up to 1 week post surgery

Time to first ambulation

Time to first ambulation of 50 feet or more, with or without the help of assist devices (i.e. walker, cane) or staff assistance.

Time frame: Up to 1 week post surgery

Ambulation distance

This data point will be measured in feet and will be determined by the distance ambulated during the patient's first ambulation attempt after surgery, regardless of the length of ambulation (This distance will be counted regardless of whether the patient reaches the 50 feet requirement to be counted as the "time to first ambulation).

Time frame: Up to 1 week post surgery

Length of hospital stay

Number of days in the hospital from postoperative day 0 to discharge

Time frame: Until discharge from hospital, up to 1 week post surgery

Patient satisfaction

Patient satisfaction score will be assessed on day of discharge as measured by a 5-point scale with 1 = terrible, 2 = poor, 3 = satisfactory, 4 = good, and 5 = excellent.

Data from ClinicalTrials.gov

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