Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain

Inclusion Criteria: 1. Ambulatory 2. History of total knee arthroplasty or revision arthroplasty in the symptomatic knee 3. Moderate to severe knee pain: pain VAS ≥50 mm 4. Knee pain resistant to at least 3 months of conservative therapy including pharmacologic therapy or intra-articular injection. 5. Absence of pregnancy at time of screening as determined by urine HCG 6. Provision of signed and dated informed consent form 7. Willing, able, and mentally competent to provide informed consent and to tolerate angiography, US, and MRI. Exclusion Criteria: An individual who meets any of the following criteria will be excluded from participation in this study: 1. History of severe peripheral arterial disease symptoms including claudication, diminished or absent lower extremity pulses, leg numbness or weakness or known arterial atherosclerosis or occlusion that would limit selective angiography 2. History of inflammatory arthropathy such as rheumatoid arthritis, spondyloarthropathies, crystal disease, gout, pseudogout, or lupus 3. Presence of non-MRI compatible devices (e.g., cardiac pacemaker). 4. Known history of anaphylaxis to iodinated or gadolinium-based contrast agents 5. BMI greater than 50 6. Renal dysfunction as defined by serum creatinine \>1.6 dl/mg or eGFR \<60 obtained within 30 days of procedure. 7. Uncorrectable coagulopathy (platelet count \< 50,000, international normalized ratio \>1.5 within 30 days of procedure 8. Active systemic or local knee infection 9. Pregnant or intent to become pregnant during the study