Argon Plasma Coagulation and Clip for the Prophylaxis of Post-polypectomy Bleeding After Hot Snare Polypectomy

Inclusion Criteria: 1. age\>18 years 2. the diagnosis of colorectal polyps is clear（Paris Ip or Ⅰsp） 3. head diameter≥ 10 mm 4. HSP indications were met and no contraindications were found 5. patients (or the legal representative/guardian) with informed consent Exclusion Criteria: 1. ASA Grade Ⅲ or above, or end-stage disease of major organs (such as malignancy, heart failure, chronic obstructive pulmonary disease, end-stage renal disease and so on) 2. coagulation dysfunction (INR ≥ 1.5, PLT \< 50×10 \^9 / L) 3. use antiplatelet drugs within 7 days before the operation, anticoagulant drugs within 5 days, and/or blood products within 30 days after the operation 4. there were other lesions in the resection site of the included polyps affecting this study, or the intestinal preparation was insufficient 5. incomplete closure of clips (complete closure: spacing between adjacent clips \< 1cm) 6. APC is used for polypectomy or intraoperative hemostasis, rather than preventing PPB 7. surgical treatment, vascular intervention, or blood products were used during the operation 8. use other methods to prevent PPB 9. the bleeding site was not confirmed by endoscopy 10. history of intestinal surgery 11. menstruation or pregnancy 12. not following medical advice 13. participated in other clinical trials and signed its informed consent