A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVSQIV in Healthy Adults

Inclusion Criteria: * Healthy male or female subjects between the ages of 18 and 55 years, inclusive, at enrollment (Younger Adults groups) or aged ≥65 years at enrollment (Older Adults groups). A healthy subject is defined as an individual who is in good general health, according to the Investigator's assessment. Chronic health conditions are acceptable if the condition is considered stable and well controlled with treatment according to the discretion of the Investigator. * Signed informed consent obtained before any trial procedures. * Expected to be compliant with protocol procedures and available for clinical follow-up through the last planned contact. * Physical examination without clinically significant findings according to the Investigator's assessment. * Body mass index (BMI) ≥18.0 and ≤32.0kg/m2. * Females: At the time of enrollment, negative human chorionic gonadotropin (hCG) pregnancy test (serum) for women presumed to be of childbearing potential on the day of enrollment. On Day 1 (pre-vaccination): negative urine pregnancy test (hCG), (only required if serum pregnancy test was performed more than 3 days before). Note: Women that are postmenopausal (defined as amenorrhea for ≥12 consecutive months prior to enrollment without an alternative medical cause) or permanently sterilized will be considered as not having reproductive potential. * Females of childbearing potential must use highly effective methods of birth control from 1 month before until 3 months after the trial vaccine administration. The following methods of birth control are considered highly effective when used consistently and correctly: * Combined (estrogen and progestogen containing) hormonal contraception associated with inhibition of ovulation (oral, intravaginal or transdermal); * Progestogen-only hormonal contraception associated with inhibition of ovulation (oral, injectable or implantable); * Intrauterine devices; * Intrauterine hormone-releasing systems; * Bilateral tubal occlusion; * Vasectomized partner; * Same sex relationships. Sexual abstinence (periodic abstinence \[e.g., calendar, ovulation, symptothermal and post-ovulation methods\] and withdrawal) are not acceptable methods. Exclusion Criteria: * Use of any investigational or non-registered product (vaccine or drug) other than the trial vaccine within 28 days preceding the trial vaccine administration, or planned use during the trial. * Receipt of any influenza vaccine within 90 days of enrollment. * Receipt of any mRNA vaccine within 2 months of enrollment. * Receipt of any other vaccines within 28 days prior to enrollment or planned receipt of any vaccine within 28 days of trial vaccine administration. * Any treatment with immunosuppressants or other immune-modifying drugs (including, but not limited to, corticosteroids, biologicals and methotrexate) for \>14 days total within 6 months prior to the trial vaccine administration or planned use during the trial, with the exception of inhaled or topically-applied steroids. For corticosteroid use, this means prednisone or equivalent, 0.5 mg/kg/day for 14 days or more. * Any medically diagnosed or suspected immunosuppressive or immunodeficient condition based on medical history and physical examination, including known human immunodeficiency virus infection. * Chronic hepatitis B virus infection and chronic hepatitis C virus infection. * History of pIMD * History of angioedema. * History of any neurological disorders or seizures including Guillain-Barré syndrome, with the exception of febrile seizures during childhood. * History of allergy to any component of CVSQIV, or to aminoglycoside or beta-lactam antibiotics. * History of any severe allergic reaction or anaphylactic reaction. * History of or current alcohol and/or drug abuse. * Administration of immunoglobulins and/or any blood products within the 3 months preceding the trial vaccine administration. * Presence or evidence of significant acute or chronic medical or psychiatric illness. * Current or past malignancy, unless completely resolved without sequelae for \>5 years. * For females: pregnancy or lactation. * Subjects with impaired coagulation or any bleeding disorder in whom an intramuscular injection or a blood draw is contraindicated. * Subjects employed by the Sponsor, Investigator or trial site, or relatives of research staff working on this trial.