The etiology of bowel obstruction is usually diagnosed by imaging techniques such as MSCTE,MRE, et al, which have some disadvantages. For example, in order to obtain better image quality, MSCTE(Multi-slices spiral computed tomography enterography) and MRE( Magnetic resonance enterography)require patients to take a large amount of intestinal contrast solution orally, while for patients with intestinal obstruction, which may further aggravate the disease. Our study team had confirmed the mid-gut TET could serve as the delivery way of contrast solution for MRE bowel preparation with better accuracy of lesion detection and lower reduction of pain in CD(Crohn's Disease) patients. In this study, contrast solution will be delivered by colonic TET placed by lower GI-endoscopy, then we will evaluate the methodology and clinical value of this kind retrograde imaging technique in patients with intestinal obstructive diseases.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
60
Delivery of contrast fluid by colonic TET Each participant will receive one delivery of 200 ml contrast fluid by colonic TET to the distal portion of the lesion. One group will be taken CT investigation, another group will be taken X-ray fluoroscopy. Imaging parameters will be collected and evaluated.
Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
The diagnostic self-confidence score
Image parameters of the lesion( i e. Location,Nature, Severity, Appearance, Fistula) will be recorded by the reader. The diagnostic self-confidence for each image parameter will be determined using a continuous five-grade scoring system from 1 to 5(1 = worst, 2=worsen, 3=normal, 4= better,5 = best). For example: The doctor's diagnostic self-confidence for Location is worsen ,then the diagnostic self-confidence score will be recorded as 2。
Time frame: immediately after CT/X-ray fluoroscopy detection,no more than 24hours.
Evaluation of comprehensive diagnostic efficiency
comprehensive diagnostic efficiency=(Location+Nature+Appearance+Fistula+Proximal lesion filled by contrast fluid). Each positive parameter will be recorded as mark 1, negative mark 0. Each participant will get up to 5 score. For example: for some one participant ,if the doctor could determine the location and nature of the lesion, however,appearance, fistula and proximal lesion filled by contrast fluid could not be determined, then ,the score of comprehensive diagnostic efficiency equals 2.
Time frame: immediately after CT/X-ray fluoroscopy detection,no more than 24hours.
Adverse reaction
Adverse reaction( abdominal pain, abdominal distention, nausea, vomiting) will be recorded and graded by score 1 to 5 according to the severity of each symptom.
Time frame: during the process, and no more than 24hours after CT/X-ray fluoroscopy detection
Tolerance
Tolerance will be evaluated by questionnaire investigation。1--Severely intolerable;2--Moderately intolerable;3--Slightly intolerable;4--Tolerable。
Time frame: during the process, and no more than 24hours after CT/X-ray fluoroscopy detection
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