The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with supportive home oral care for the treatment of periodontal disease. Patients with bilateral periodontal pathological sites will undergo professional dental hygiene with ultrasonic handpiece (Piezon EMS with PerioSlim inserts) followed by manual instrumentation with Gracey curettes and application of erythritol Airflow powders. Then, patients will be randomly divided into two groups according to a split-mouth design: the Control Group will undergo a split-mouth application of chlorhexidine gel 1% for quadrants 1/3 (or 2/4), while for the Trial Group Ozoral Pro for quadrants 2/4 (or 1/3) will be used. Patients will use the products at home with one daily application for the following 14 days after the visits. The Trial Group will use Ozoral Gel for home applications. The following indexes will be assessed at baseline, T1 (1 month), T2 (3 months) and T3 (6 months): recession, PPD, BoP %, CAL, PCR %. Contextually, the application of the two gels will be performed.
The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with supportive home oral care for the treatment of periodontal disease comparing chlorhexidine and ozone gels. Patients with bilateral periodontal pathological sites will undergo professional dental hygiene with ultrasonic handpiece (Piezon EMS with PerioSlim inserts) followed by manual instrumentation with Gracey curettes and application of erythritol Airflow powders. Then, patients will be randomly divided into two groups according to a split-mouth design: * Control Group: application of chlorhexidine gel 1% for quadrants 1/3 (or 2/4) * Trial Group: administration of Ozoral Pro for quadrants 2/4 (or 1/3). Patients will use the products at home with one daily application for the following 14 days after the visits. The Trial Group will use Ozoral Gel for home applications. The following indexes will be assessed at baseline, T1 (1 month), T2 (3 months) and T3 (6 months): recession, PPD, BoP %, CAL, PCR %. Contextually, the application of the two gels will be performed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
30
In-office and domiciliary use of chlorhexidine for 14 days.
In-office administration of Ozoral Pro and domiciliary use of Ozoral gel for 14 days.
Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, Italy
Change in R - Gingival recession
Distance (in mm) between the gingival margin and the amelo-cemental junction.
Time frame: Time Frame: baseline, 1, 3 and 6 months after baseline
Change in PPD - Probing Pocket Depth
Evaluation (in mm) of the depth of the gingival sulcus, through a millimeter periodontal probe; it is detected from the gingival margin to the bottom of the gingival sulcus or periodontal pocket, evaluated at 6 sites.
Time frame: Time Frame: baseline, 1, 3 and 6 months after baseline
Change in Bleeding on Probing (BOP%)
Dichotomous scoring (yes/no) of bleeding sites
Time frame: Time Frame: baseline, 1, 3 and 6 months after baseline
Change in Plaque Control Record (PCR%)
% assessment of the amount of plaque on dental surfaces; it is detected on 4 surfaces: distal, mesial, vestibular, lingual / palatal. The number of sites with plaque is divided by the total number of sites available in the mouth and multiplied by 100. Results indicate the index as a percentage.
Time frame: Time Frame: baseline, 1, 3 and 6 months after baseline
Change in Dental mobility (Miller, 1985)
Scoring criteria * Grade 0: oscillation within 0.2 mm; the teeth move naturally and there are no mobility problems; * Grade I: horizontal mobility of the tooth from 0.2 to 1 mm; * Grade II: horizontal mobility of the tooth from 1 to 2 mm; * Grado III: horizontal mobility equal to or greater than 3 mm or vertical mobility of the tooth.
Time frame: Time Frame: baseline, 1, 3 and 6 months after baseline
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