Development of Machine Learning Models for the Prediction of Complications After Colonic, Colorectal and Small Intestine Anastomosis in Psychiatric and Non-psychiatric Patient Collectives (P-Study)

Dr. Med Anas Taha10,000 enrolled

Overview

Our study aims to lay the basis for a predictive modeling service for postoperative complications and prolonged hospital stay in patients suffering from psychiatric diseases undergoing colorectal surgery. Furthermore, we aim to investigate the impact of preoperative Risk factors, psychiatric and psychosomatic diseases on the outcomes of colorectal surgery and the complications after colorectal surgeries like anastomosis insufficiency via predictive modeling techniques The service mentioned above will be publicly available as a web-based application

Study Type

OBSERVATIONAL

Enrollment

10,000

Conditions

Postoperative Complications Psychosomatic Disorder Psychiatric Disorder Cancer Diverticulitis Morbus Crohn Colitis Ulcerosa Anastomotic Leak

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Colocolic, colorectal and small intestine anastomosis * Neoplasia, * Diverticulitis * Mesenteric ischemia * Iatrogenic or traumatic perforation * Inflammatory bowel disease Exclusion Criteria: * Patients \<18 years * Patients suffering from recurrent colorectal cancer bearing * Peritoneal carcinomatosis or unresectable metastatic disease at the time of bowel resection and anastomosis will be excluded. * Patients who cannot be followed up on for more than six weeks after surgery

Outcomes

Primary Outcomes

Anastomotic insufficiency/leakage

Predictive model with an app for the development of anastomosis insufficiency based on the risk factors.

Time frame: From index surgery up to six weeks postoperatively

Complication after surgery/ Comprehensive Complication Index/ Clavian Dindo Score

Impact of psychatric and psychosomatic disorders are having higher complication rates

Time frame: From index surgery up to six weeks postoperatively

Length of Hospital Stay (in Days)

Impact of psychatric and psychosomatic disorders are having longer hospitalization

Time frame: From surgery up to 12 weeks postoperatively

Intraoperative influid manangment

Impact of Intraoperative influid on the development of anastomotic insuffiency

Time frame: Time Frame: From index surgery up to six weeks postoperatively

Development of a preoperative score for morbidity/mortality in colorectal surgery

Check the risk for morbidity/mortality in colorectal surgery

Time frame: From index surgery up to six weeks postoperatively

Development of Machine Learning Models for the Prediction of Complications After Colonic, Colorectal and Small Intestine Anastomosis in Psychiatric and Non-psychiatric Patient Collectives (P-Study)

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts