Structural and Functional Characterization of Rare Ocular Diseases

Barcelona Macula Foundation50 enrolled

Overview

Rare ocular diseases (ROD) are a heterogeneous group of ocular diseases that affect very few people and, generally, for which no tretament is available. An important subgroup of these diseases are inherited retinal degenerations. In this study we focus on understanding the natural history of different ROD that affect the posterior segment.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Retinitis Pigmentosa Stargardt Disease 1 Best Disease Pattern Dystrophy of Macula Choroideremia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female 18 years or older with a diagnosis of a ROD affecting the posterior segment * Patients able to undergo all required ophthalmic exams * Patients able and willing to sign an informed consent Exclusion Criteria: * Patients with other concomitant posterior segment disorders * Patients taking drugs known to affect the retina and/or optic nerve * Patients that underwent an intraocular surgery (aside from phacoemulsification with intraocular lens implantation), corneal or glaucoma surgery * Patients who have participated in the past 12 months or that are currently participating in clinical trials for an ocular disease

Locations (1)

Institut de la màcula

Barcelona, Spain

RECRUITING

Outcomes

Primary Outcomes

Change in best corrected visual acuity

Change from baseline in BCVA

Time frame: Year 2 as compared to baseline

Secondary Outcomes

Change in mean macular sensitivity

Change from baseline in mean macular sensitivity on microperimetry

Time frame: Year 2 as compared to baseline

Change in retinal thickness

Change from baseline in central subfield retinal thickness on OCT

Time frame: Year 2 as compared to baseline

Central Contacts

Marc Biarnes, PhD

CONTACT

+34935950155 mbiarnes@barcelonamaculafound.org

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.