Mapping 3D Bladder

University Health Network, Toronto

Overview

This is a single centre, single arm feasibility study assessing the feasibility of using computer vision methods to recreate the 3D bladder shape and to then map the cystoscopy images onto this bladder shape. If feasible, this 3D reconstructed shape would be spatially registered to radiological images (CT, MR) that are then used during radiation treatment planning. This analysis would not be used for making any clinical treatment decisions on the patient.

Study Type

OBSERVATIONAL

Conditions

Bladder Cancer

Interventions

CystoscopyPROCEDURE

Standard of care cystoscopy procedure

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18 years of age or older. * Clinical suspicion or histologic diagnosis of bladder tumour suitable for endoscopic evaluation. * Intention to treat using external beam radiation therapy as part of standard of care. * Ability to provide written informed consent to participate in the study. Exclusion Criteria: * Prior complete or partial radiation therapy to bladder. * Contraindications to radiation therapy as determined by the treating physician. * Concurrent illness or condition that precludes subject from undergoing endoscopy or CT scanning.

Locations (1)

Princess Margaret Cancer Centre

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

Video recording of Cystoscopy

To determine the feasibility of using bladder endoscopic video images to reconstruct the three-dimensional shape of the bladder based on computer visions methods that employ feature extraction and triangulation and to map the endoscopy images onto the recreated 3D surface.

Time frame: At study completion, up to 2 years

Contouring of 3D bladder rendering

To determine the feasibility of contouring the mucosal disease on the 3D bladder rendering.

Time frame: At study completion, up to 2 years

Registering bladder shape

To determine the feasibility of registering the bladder shape to a CT/MR scan of the patient using deformable shape methods.

Time frame: At study completion, up to 2 years

Data from ClinicalTrials.gov

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