Diffusion-tensor Imaging in Brain Tumors Evaluation

George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures100 enrolled

Overview

Primary and secondary brain tumors are challenging pathologies regarding diagnosis and treatment. MRI is widely used in the imaging evaluation and surgical planning, due to its spatial resolution and ability of tissular characterization. In this study patients with suspected brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation. By analyzing collected data from MRI evaluation and patient records regarding surgical and histopathological data our aim is to investigate derived imaging biomarkers with impact in the surgical planning and rehabilitation of the patients.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Diffusion Tensor Imaging Tractography MRI

Interventions

MRIDIAGNOSTIC_TEST

In this study patients with suspected primary and secondary brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * brain tumors confirmed by routine MRI evaluation * surgical treatment with histopathological diagnosis Exclusion Criteria: * MRI contraindications * past or present neurological or neurosurgical condition, beside the tumor * pregnancy

Outcomes

Primary Outcomes

Tract damage

Assess the damage of tracts at baseline preoperative

Time frame: 3 months

Secondary Outcomes

Craniotomy size

Assess the size of craniotomy in patients with postoperative CT follow-up